Fertility and assisted reproduction clinic · Mexico City and Puebla

We listen before we recommend a treatment.

What you want for your life deserves a personalized medical evaluation by specialists in human reproduction and fertility, with an on-site laboratory and psychological support from start to finish.

Your location Polanco Mítikah Angelópolis
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Meet our specialists

An egg with its zona pellucida and corona radiata, in glass. Scroll down to see its first days in our laboratory

How we support you

To us, every patient is a unique story — not a statistic.

We know that assisted reproduction treatment is a complex process, which is why every case begins the same way: with time to listen to you, assess your situation as a whole and explain your options clearly and without rushing.

  1. We listen

    Your evaluation visit starts with your story and your goals. Your doctor reviews your case and explains which treatment suits you best, if you need one at all.

  2. Our own laboratory

    We have our own laboratory to carry out, in a timely way, the tests your process requires. Among the most common:

    • Hormone panel
    • Anti-Müllerian hormone
    • Infectious disease screening
    • Semen analysis
    • Semen culture
    • Sperm preparation (capacitation)
    • Sperm DNA fragmentation
    • Testicular biopsy analysis

  3. Always with you

    We are present at every stage of your process, because we know that infertility doesn’t only affect the body — it also weighs on you emotionally. That is why, at Procrea, you have a multidisciplinary team that supports you in a comprehensive way:

    • Psychology and coaching — emotional support throughout the process
    • Nutrition — dietary guidance aligned with your treatment
    • Gynecology — specialized follow-up and care
    • Maternal-fetal medicine — specialized care during pregnancy
    • Sperm bank — sperm preservation and donation

    Portrait of Verónica Rubio Bonilla, PsychologistVerónica Rubio Bonilla, PsychologistPsychologist and coach · Polanco

A second chance

Already tried elsewhere? Here we start by understanding what happened.

Many patients come to Procrea after a treatment that didn’t work. We don’t start from scratch, and we don’t repeat things just to repeat them: your specialist reviews what you have already done and then walks you through the options available in your case.

I’d like a second opinion WhatsApp

No promises: every case is different, and your doctor tells you clearly what is possible in yours.

  1. We review what you’ve already done

    Your previous tests and treatments are part of the evaluation. Bring them to your first appointment.

  2. Tests

    Depending on each case, we evaluate ovulation and hormonal balance, ovarian reserve, the condition of the uterus and fallopian tubes, the endometrium and male fertility.

  3. Techniques for these cases

    When your doctor recommends them: endometrial tests such as ERA, EMMA and ALICE (receptivity, microbiome and chronic endometritis), assisted hatching after implantation failure, PGT-A (preimplantation genetic testing for aneuploidy), or egg donation after repeated unsuccessful IVF cycles.

  4. With specialists who keep their knowledge up to date

    Board-certified doctors and reproductive medicine specialists, trained in Mexico and abroad, committed to continuing education and the latest advances in reproductive medicine. You choose who to book with.

Our laboratory

Five days in the lab.

From day 0 to day 5 in our laboratory, and what comes after, with the techniques we use at Procrea.

  1. 01Day 0

    Fertilization: IVF or ICSI

    After egg retrieval, the egg arrives in the laboratory. In conventional IVF it is placed together with sperm so that one can fertilize it; with ICSI, the embryologist chooses one sperm for its motility and shape and places it inside the egg with an extremely fine pipette. PICSI makes that selection using tests that are less subjective than observation.

    Techniques: ICSI · PICSI

  2. 02Day 1

    Zygote: two pronuclei

    Between 16 and 18 hours later, fertilization is confirmed: two pronuclei can be seen inside the egg, one carrying the egg’s genetic material and the other the sperm’s. It is now a zygote, and the laboratory monitors it closely in incubators with controlled conditions.

  3. 03Day 2

    From 2 to 4 cells

    The zygote divides into two cells and then into four, which is what is expected on day 2. With sequential culture it moves through different media, each with the nutrients it needs at that stage.

    Technique: Sequential culture

  4. 04Day 3

    About 8 cells

    On day 3, about eight cells are expected. The embryologist looks at their number, symmetry, fragmentation and growth rate. Some embryos are transferred on this day; others stay in culture until day 5.

    Technique: Sequential culture

  5. 05Day 4

    Morula

    The cells compact and can no longer be told apart one by one: the embryo looks like a tiny mulberry, which is where its name comes from.

  6. 06Day 5

    Blastocyst, inside its zona pellucida

    A fluid-filled cavity, the blastocoel, appears, and the cells separate into two groups: the inner cell mass, which will give rise to the embryo, and the trophectoderm, which will become part of the placenta. Everything is still inside the zona pellucida: one sphere within another. If your doctor recommends it, PGT-A (preimplantation genetic testing for aneuploidy) is performed at this stage; embryos that are not transferred can be vitrified at −196 °C.

    Techniques: Sequential culture · PGT-A · Cryopreservation

  7. 07Day 3 or day 5

    Embryo transfer

    Using a thin catheter, guided by ultrasound, the embryo is placed in the uterus; if it was cultured to the blastocyst stage, this is usually on day 5, still inside its zona pellucida. To assess the endometrium before that day, tests such as ERA, EMMA and ALICE (endometrial receptivity, microbiome and chronic endometritis) are available.

    Techniques: Embryo transfer · ERA

  8. 08Now in the uterus

    Hatching

    The blastocyst expands, the zona pellucida thins and opens, and the embryo emerges from it: without hatching, it cannot implant. When your doctor recommends it, a tiny opening is made in the zona in the laboratory with laser micropulses before the transfer (assisted hatching).

    Technique: Assisted hatching

  9. 095 to 7 days after fertilization

    Implantation

    The blastocyst attaches to the endometrium at the pole where the inner cell mass is located and begins to embed in the uterine lining. The pregnancy test is done about two weeks after the transfer.

  10. 10Afterward

    Where a story begins

    If the embryo implants, a pregnancy begins, and what follows is no longer counted in laboratory days but in weeks. Every case is different: your doctor explains clearly what to expect in yours.

Abstract illustration, not a clinical depiction. Timings are the standard embryology references (ESHRE/ALPHA consensus); every embryo and every case is different.

Treatments in depth

Learn about our treatments.

We offer lower-complexity treatments, such as timed intercourse and artificial insemination, and higher-complexity ones, such as in vitro fertilization and egg donation. The most suitable option for your case is defined based on your medical evaluation. Here we explain what each one involves.

Lower complexity

Timed intercourse

What it is

Your fertile window is identified and intercourse is planned for those days, to increase the chances of conceiving naturally.

Who it is for

  • Couples with mild fertility problems or unexplained infertility.
  • When there is no clear indication for more advanced techniques, such as insemination or IVF.
  • As a first option, before considering more invasive treatments.

What the process involves

  1. Menstrual cycle trackingBy observing cervical mucus, basal body temperature or ovulation tests.
  2. Fertile daysThe days with the best chances are identified.
  3. Planned intercourseOn those specific days.
  4. Re-evaluationIf there is no pregnancy after several cycles, your specialist assesses the next step.

Frequently asked questions

Does it work the same for every couple?

No. The result varies depending on the cause of infertility and other factors for each couple. That is why, if there is no pregnancy after several cycles, it is a good idea to go back to your specialist.

What is the ideal age to start treatment?

Age matters: after 35, ovarian reserve gradually declines. Even so, it is not the only factor. Get in touch and we will guide you based on your case.

Book an evaluation WhatsApp

In Puebla? Message Angelópolis

Lower complexity

Intrauterine insemination (IUI)

What it is

Previously processed semen is placed directly in the uterus during your fertile window, so the sperm reach the egg more easily. It is also called artificial insemination or IUI.

Who it is for

  • Polycystic ovary syndrome, endometriosis or abnormal semen parameters, when they are not severe.
  • If you want to become a mom without a partner, using a sample from our sperm bank.
  • An evaluation visit is needed before starting: the treatment depends on those conditions not being severe.

What the process involves

  1. Controlled ovarian stimulationTo prepare for ovulation.
  2. Ovulation monitoringTo find the right moment.
  3. Semen collection and processingIn the laboratory, the same day.
  4. InseminationThe processed semen is placed in the uterus.
  5. Follow-up and pregnancy testYour doctor is with you during the wait.

Frequently asked questions

How do I know if I’m a candidate for treatment?

If you have been trying to conceive for more than a year, if you are over 35 and want a baby, or if you have had recurrent miscarriages, it is a good idea to see one of our specialists for guidance.

Can I do it without a partner?

Yes. If you are single and want to be a mom, you can use a sample from our sperm bank. Your doctor explains the process during your evaluation.

Which sexually transmitted infections affect fertility?

Chlamydia, gonorrhea and HPV are the main ones, in both men and women. That is why we run the necessary tests before recommending a treatment.

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In Puebla? Message Angelópolis

Higher complexity

In Vitro Fertilization (IVF)

What it is

The egg is fertilized outside the body, in our laboratory, using different techniques. The embryo with the greatest implantation potential is then placed in the uterus.

Who it is for

  • Problems with the fallopian tubes, including a previous tubal ligation (“tubes tied”).
  • Few eggs available, low ovarian reserve, or conditions that affect ovarian function.
  • Low sperm count, or sperm quality that is not enough for natural fertilization.
  • Recurrent miscarriages or previous inseminations that didn’t work.

What the process involves

  1. Ovarian stimulationHormonal medication so the eggs reach their final maturation.
  2. Egg retrievalThe contents of the ovarian follicles are aspirated and analyzed in the laboratory.
  3. Semen preparationThe best-quality sperm are separated and the seminal plasma is removed.
  4. FertilizationConventionally, or with ICSI or PICSI, which select the sperm one by one.
  5. Embryo transferThe embryo with the greatest implantation potential is chosen and placed in the uterus.

Frequently asked questions

I had a tubal ligation. What are my options?

After a tubal ligation, our specialists recommend In Vitro Fertilization, which avoids the need for surgery. In your evaluation they explain how it applies to your case.

How much does IVF cost?

The price is set at your consultation, because every case is different: it depends on the medication, tests and visits you need.

What is the difference between ICSI and PICSI?

Both place a selected sperm inside the egg. In ICSI the embryologist chooses it for its motility and shape; in PICSI the selection relies on tests that are less subjective than observation, in order to choose the most mature sperm.

Book an evaluation WhatsApp

In Puebla? Message Angelópolis

Higher complexity

Egg donation

What it is

Eggs donated by a fertile woman are used so that another woman or couple can pursue a pregnancy when their own eggs are not viable or are of very low quality.

Who it is for

  • Premature ovarian insufficiency.
  • Advanced maternal age.
  • Genetic abnormalities or hereditary diseases.
  • Diminished egg quality.
  • Repeated unsuccessful IVF cycles.

What the process involves

  1. Donor selectionShe must meet the established requirements.
  2. SynchronizationThe donor’s and recipient’s cycles are coordinated with hormonal treatment.
  3. Egg retrievalThe donor’s mature eggs are retrieved.
  4. Fertilization and cultureIn the laboratory, until good-quality embryos are obtained.
  5. Embryo transferInto the recipient’s uterus.
  6. Follow-up and pregnancy testTo assess the outcome of the procedure.

Frequently asked questions

Who can donate eggs?

Women aged 18 to 29, physically and mentally healthy, with no malformations, infections or hereditary genetic diseases, who undergo testing for HIV, hepatitis B and C, VDRL and karyotype.

Does donating affect the donor?

Donating does not affect her future egg production or reduce her chances of becoming pregnant.

How do I know which treatment is best for me?

Through a diagnostic evaluation by our specialists. Every case is different, and the evaluation is the first step.

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In Puebla? Message Angelópolis

Fertility preservation

Egg and sperm freezing (vitrification)

What it is

Eggs are retrieved and frozen in liquid nitrogen. The temperature drops so fast that no ice crystals form that could damage the cells, so you can postpone motherhood until you decide the time is right.

Who it is for

  • You want to be a mom in the future, but not now.
  • You have a condition that may affect your fertility.
  • You are about to receive cancer treatment, or treatment for another illness, that could affect it.
  • You are about to have In Vitro Fertilization.
  • The best age to do it is before 35: with age, both the quality and the number of eggs decline.

What the process involves

  1. Ovarian stimulationTo obtain more mature eggs.
  2. RetrievalThe eggs are collected.
  3. Egg freezingThey are stored in liquid nitrogen at −196 °C.
  4. When you decideTo pursue a pregnancy with them, IVF with ICSI or PICSI is performed.

Frequently asked questions

How long can they stay vitrified?

As long as necessary. The process does not affect the quality of the eggs.

Can sperm be preserved too?

Yes. In our sperm bank, sperm is frozen with cryoprotectants and liquid nitrogen, to be used later in IVF or insemination.

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In Puebla? Message Angelópolis

Who will guide your treatment?

Your doctor is chosen at your evaluation, based on your case and your location. Here is the medical team at each location:

Polanco9 doctors and a psychologistMítikah2 doctorsAngelópolis3 doctors

Your path

Every journey to parenthood is different.

Every kind of family, at every stage. Choose yours and we’ll show you what we can offer in your case.

Your path · Becoming a mom with a male partner

We begin by evaluating both partners: she sees a gynecologist, and he has tests such as semen analysis and, if needed, a visit with our urologist and andrologist. Depending on the case, the path may be timed intercourse, insemination or In Vitro Fertilization.

See In Vitro Fertilization WhatsApp

More about IVF

Your path · Becoming a mom on your own

If you are single and want to be a mom, you can do it with a sample from our sperm bank, using intrauterine insemination or, if your case calls for it, In Vitro Fertilization.

See intrauterine insemination WhatsApp

More about the sperm bank

Your path · Becoming a mom with a female partner

With the ROPA method (also called reciprocal IVF or shared motherhood), both of you take part: one provides the eggs and is the genetic mother; the other receives the embryo and is the gestational mother. The sperm can come from a known donor or from our sperm bank.

See In Vitro Fertilization WhatsApp

More about the ROPA method

Your path · Plan ahead for motherhood

If now is not the time, you can freeze your eggs and decide later; the best age to do it is before 35. Men can also preserve their fertility in our sperm bank.

See egg freezing WhatsApp

More about preserving fertility

Your path · Becoming a mom again

Did you have a procedure to prevent pregnancy, and now a baby is what you want most? After a tubal ligation, our specialists recommend In Vitro Fertilization. It all starts with an evaluation.

See In Vitro Fertilization WhatsApp

More about becoming a mom again

Medical team

Meet the people behind Procrea.

Specialists in human reproduction and fertility, with the training, certifications and clinical experience to evaluate your case. Choose your specialist: each has a page with their background and a way to book your first appointment.

  • 3 AMMR presidentsThree of our specialists have served as president of the Mexican Association of Reproductive Medicine (AMMR). Dr. Sergio Villalobos Acosta currently holds the presidency of the institution.
  • COMEGODoctors certified by the Mexican Council of Specialists in Obstetrics and Gynecology, with training in human reproductive biology.
  • Licenses you can verifyEach profile lists the professional licenses (cédulas) that Procrea publishes, so you can verify them in Mexico’s National Registry of Professionals.
  • Always learningReproductive medicine specialists trained at the National Institute of Perinatology (INPer) and UNAM, and at centers such as Oxford, Technion (Israel), Cleveland Clinic, Texas Woman’s Hospital, UCSD and UCLA; members of the AMMR, ASRM and ESHRE, and conference speakers.

PolancoMexico City

MítikahMexico City

AngelópolisPuebla

Your first appointment

What happens at your first appointment?

This is an evaluation visit: your specialist gets to know your case before recommending anything.

  1. Listening to youYour history: how long you have been trying, your age, your medical background, any previous pregnancies or losses, and the treatments you have already had.
  2. Evaluating what is neededDepending on your case: ovulation and hormonal function, ovarian reserve, the uterus and fallopian tubes and, if relevant, male fertility. Not everyone needs the same tests.
  3. Explaining your optionsWith that information, your doctor tells you what is happening and what options you have, if you need a treatment at all. Tests are done in the clinic’s own laboratory.
  4. Staying by your sideIf you decide to move forward, your doctor stays with you at every step, with psychological and nutrition support whenever you need it.
  • In person at any of the three locations, or online if you can’t come to the clinic.
  • Already treated at another clinic? Your previous tests and treatments are part of the evaluation.
  • Your spot is reserved with a deposit. The cost depends on the doctor and the location, and the team confirms it when you book.
Book your first appointmentWhatsApp

Locations

Three locations. Choose the one closest to you.

Polanco and Mítikah share our main WhatsApp, +52 55 2246 1259; Angelópolis has its own, +52 222 435 7345. Each button opens a WhatsApp message already filled in with your location.

Tower of Hospital San Ángel Inn, home of the Mítikah location: a pale green glass facade with curved bands, against a blue sky

MítikahMexico City

Av. Río Churubusco #601, Hospital San Ángel Inn, Office Tower 2, lobby level, unit 1, Xoco, Benito Juárez, postal code 03330, Mexico City

Monday to Friday
10:00 a.m. to 6:00 p.m.
Saturday
8:00 a.m. to 2:00 p.m.
WhatsApp Mítikah Get directions

WhatsApp +52 55 2246 1259

AngelópolisPuebla

Paseo Ópera #4, Escala building, unit 109, 1st floor, Sonata, Lomas de Angelópolis, postal code 72830, Puebla

Monday to Friday
9:00 a.m. to 8:00 p.m.
Saturday
9:00 a.m. to 2:00 p.m.
WhatsApp Angelópolis Get directions

WhatsApp +52 222 435 7345

Blog

A new article every week.

Causes of infertility, pregnancy and fertility, explained by our team. These are the most recent; the articles are in Spanish.

See the whole blog (in Spanish)
  1. Causes of infertilityTrying to conceive with insulin resistance?

    It is an increasingly common metabolic condition and one of those that can have the greatest impact on female fertility. Many women have it without knowing.

  2. InfertilityWhy can’t I get pregnant? When to see a fertility specialist
  3. PregnancyWhen should you start taking folic acid before pregnancy?
  4. FertilityThe corpus luteum: what it is and its role in pregnancy

Book your appointment

Book your evaluation.

Before any treatment, an evaluation visit: your doctor reviews your case and explains your options. Enter your details and we will open the WhatsApp chat for your location with your message ready, so you can choose a day and time.

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